Experiments that help improve digestion

Supplements, protocols, and habits for falling asleep and staying asleep, organized by what worked best for users

Supplements, protocols, and habits for improving digestion and addressing gut symptoms, organized by what worked best for users

The aggregate picture

What we're seeing across everyone tracking digestion

Digestive issues are one of the most common reasons people come to Coco.

1,269
experiments started
58%
completion rate
35%
noticed a change
20%
made it routine
The full digestion library

All digestion experiments (10)

EmergingSupplement

NAC for liver protection

NAC is the standard hospital treatment for acetaminophen overdose, but the same glutathione-replenishing mechanism makes lower-dose NAC a rational liver support for regular acetaminophen users.

55% noticed a change181 tried
EstablishedDietary

Soluble fiber for IBS

Psyllium (soluble fiber) consistently improves overall IBS symptoms, while insoluble fiber like wheat bran frequently worsens them, and the amount you add matters as much as the type.

49% noticed a change165 tried
EmergingSupplement

A digestive enzyme for wine, aged cheese, and leftovers

A digestive enzyme taken right before meals, not daily, for people whose GI symptoms flare after fermented foods, wine, or leftovers.

42% noticed a change63 tried
ModerateProtocol

Abdominal massage for constipation

A specific clockwise massage pattern that follows the colon's anatomy has real evidence for constipation, but the direction and path are what make it work.

37% noticed a change182 tried
EstablishedProtocol

CBT for IBS

A large randomized trial found CBT for IBS significantly outperformed standard care and medication alone, with benefits maintained at 12-month follow-up.

33% noticed a change74 tried
ModerateSupplement

Probiotics for IBS

Probiotics collectively improve IBS symptoms in meta-analyses, but the effect is strain-specific, and most generic probiotic products don't use the studied strains.

31% noticed a change177 tried
ModerateSupplement

Mastic gum for digestion

A traditional Mediterranean remedy with a real randomized trial behind it for stomach pain, bloating, and heartburn.

30% noticed a change121 tried
ModerateProtocol

Slow breathing before meals

Slow breathing before eating activates the vagus nerve fibers that govern digestion, the opposite of the stressed state most people eat in.

27% noticed a change76 tried
ModerateLifestyle

Meal spacing for digestion

A housekeeping wave clears bacteria from the small intestine every 90 to 120 minutes, but only during fasting, and snacking shuts it off.

26% noticed a change114 tried
EstablishedProtocol

Low-FODMAP for IBS

Most people treat low-FODMAP as permanent restriction, but the structured reintroduction phase is the actual therapeutic point of the protocol.

21% noticed a change116 tried
The top experiment

NAC for liver protection, in practice

181
started
68%
completed
55%
noticed a change
32%
made it routine

Self-reported by Coco members. Not a clinical outcome.

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Educational content only. Not medical advice. Talk to a clinician before changing treatment.