Experiments that help improve your metabolic health

Studies consistently find that lower glycine levels are associated with insulin resistance, and supplementing it improves insulin response in people with metabolic dysfunction.

50% noticed a change295 tried

Moderate◆Supplement

Myo-inositol for insulin resistance

One of the best-evidenced options for the insulin-resistance side of PCOS, but most people who've heard of it are using the wrong ratio.

49% noticed a change221 tried

Moderate◆Supplement

Magnesium for insulin resistance

Magnesium is required for insulin signaling to work properly, and low magnesium and insulin resistance can feed each other in a cycle.

48% noticed a change143 tried

Moderate◆Supplement

Alpha-lipoic acid for blood sugar

Alpha-lipoic acid improves insulin sensitivity through antioxidant and mitochondrial mechanisms, with randomized trials finding 15-25% reductions in fasting glucose in insulin-resistant populations.

43% noticed a change186 tried

Emerging◆Supplement

Chromium for blood sugar

Chromium supplementation helps insulin work better, but the honest picture is that the benefit is small and depends heavily on whether you're deficient to begin with.

41% noticed a change232 tried

Established◷Protocol

Food order for blood sugar

Eating vegetables and protein before your carbs, same meal, same amount, can cut your glucose spike by 30-40%.

38% noticed a change303 tried

Moderate◉Dietary

Vinegar before meals for blood sugar

A tablespoon or two of any vinegar, diluted and taken before a carb-heavy meal, measurably blunts the glucose and insulin spike that follows.

38% noticed a change228 tried

Established◷Protocol

A short walk after eating

A 10-minute walk right after eating lowers your glucose spike more than a longer walk taken later in the day.

35% noticed a change180 tried

Moderate◉Dietary

A small protein preload before carbs

A small amount of protein, like whey, eaten 15-30 minutes before a starchy meal, both blunts the glucose spike and helps you feel fuller.

32% noticed a change189 tried

Moderate◆Supplement

Berberine for blood sugar

One of the most-studied natural compounds for insulin resistance, with a mechanism that overlaps a common diabetes drug, and real interaction risks to know about.

31% noticed a change166 tried

Moderate◆Supplement

Selenium and thyroid function

Selenium is essential for thyroid hormone metabolism, and deficiency is relatively common in certain regions and diets, but unlike most minerals, exceeding the safe upper limit is genuinely harmful.

31% noticed a change250 tried

Emerging◉Dietary

Ceylon vs. cassia cinnamon

The blood sugar evidence for cinnamon is modest, but the real issue is that most grocery-store cinnamon is a different, less safe species entirely.

28% noticed a change285 tried

Moderate◉Dietary

Cooling your rice or potatoes before eating

Cooking then refrigerating potatoes, rice, or pasta converts some of the starch into a fiber your body can't fully absorb, lowering the glycemic impact of the exact same food.

26% noticed a change237 tried

Emerging◷Protocol

Soleus pushups

A 2022 study found that a small, seated calf-raise motion, done at your desk, roughly halved post-meal glucose without standing up or breaking a sweat.

26% noticed a change181 tried

Moderate◷Protocol

Why the same meal spikes your blood sugar more at night than in the morning

Your body handles the exact same carbohydrate differently depending on the time of day, and shifting your biggest meal earlier can meaningfully improve blood sugar control.

22% noticed a change332 tried

The top experiment